Publications

Maurya, M.R., Nandi, M., Kumar, N., Avecilla, F. 2024. Nitrogen-Bridged Symmetrical Homogeneous and Heterogeneous Binuclear Dioxidomolybdenum(VI) Complexes and Their Catalytic Potential for Efficient Synthesis of 2-Amino-3-Cyano-4H-Chromenes/Pyrans. Chemistry.
15:e202400631. https://doi.org/10.1002/chem.202400631. 

Maurya, M.R., Kumar, N., Avecilla, F. 2024 Controlled Modification of Triaminoguanidine-Based μ₃ Ligands in Multinuclear [V^IVO]/[V^VO₂] Complexes and Their Catalytic Potential in the Synthesis of 2-Amino-3-cyano-4H-pyrans/4H-chromenes. Inorg Chem. 63(5):2505-2524. https://doi.org/10.1021/acs.inorgchem.3c03704. 

Bessa, M.J., Brandão, F., Rosário, F., Moreira, L., Reis, A.T., Valdiglesias, V., Laffon, B., Fraga, S., Teixeira, J.P. 2023. Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models.Journal of Toxicology and Environmental Health, Part B. https://doi.org/10.1080/10937404.2023.2166638.

Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo’ CD, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A. 2023. Measuring DNA damage with the comet assay: a compendium of protocols. Nature Protocols. https://doi.org/10.1038/s41596-022-00754-y.

Pilon, A., Avecilla, F., Mohai, M., Enyedy, É.A., Rácz, B., Spengler, G., Garcia, M.H., Valente, A. 2023. First iron(II) organometallic compound acting as ABCB1 inhibitor. Eur J Med Chem. 256:115466. https://doi.org/10.1016/j.ejmech.2023.115466.

Dömötör, O,, Teixeira, R,G,, Spengler, G,, Avecilla, F., Marques, F., Lenis-Rojas, O.A., Matos, C.P., de Almeida, R.F.M., Enyedy, É.A., Tomaz, A.I. 2023. Ruthenium (ii) polypyridyl complexes with benzothiophene and benzimidazole derivatives: synthesis, antitumor activity, solution studies and biospeciation.  J Inorg Biochem. 238:112058.   https://doi.org/10.1016/j.jinorgbio.2022.112058.

Møller, P., Azqueta, A., Collia, M., Bakuradze, T., Richling, E., Bankoglu, E.E., Stopper, H., Bastos, V.C., Langie, S., Jensen, A., Ristori, S., Scavone, F., Giovannelli, L., Wojewódzka, M., Kruszewski, M., Valdiglesias, V., Laffon, B., Costa, C., Costa, S., Teixeira, J.P., Marino, M., Del Bo. C., Riso, P., Zheng, C., Shaposhnikov, S., Collins, A. 2023. Inter-laboratory variation in measurement of DNA damage by the alkaline comet assay in the hCOMET ring trial. 25:gead014.  https://doi.org/10.1093/mutage/gead014.

Møller, P., Azqueta, A., Sanz-Serrano, J., Bakuradze, T., Richling, E., Bankoglu, E.E., Stopper, H., Bastos, V.C., Langie, S., Jensen, A., Scavone, F., Giovannelli, L., Wojewódzka, M., Kruszewski, M., Valdiglesias, V., Laffon, B., Costa, C., Costa, S., Teixeira, J.P., Marino, M., Del Bo. C., Riso, P., Zheng, C., Shaposhnikov, S., Collins, A. 2023. Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results. 26:gead015. https://doi.org/10.1093/mutage/gead015.

Maurya, M,R., Kumar, N., Avecilla, F. 2023. Mononuclear/Binuclear [VIVO]/[VVO2] Complexes Derived from 1,3-Diaminoguanidine and Their Catalytic Application for the Oxidation of Benzoin via Oxygen Atom Transfer. ACS Omega.8(1):1301-1318. https://doi.org/10.1021/acsomega.2c06732.

Møller, P., Azqueta, A., Rodriguez-Garraus, A., Bakuradze, T., Richling, E., Bankoglu, E.E., Stopper, H., Bastos, V.C., Langie, S.A.S., Jensen, A., Ristori, S., Scavone, F., Giovannelli, L., Wojewódzka, M., Kruszewski, M., Valdiglesias, V., Laffon, B., Costa, C., Costa, S., Teixeira, J.P., Marino, M., Del Bo’ C., Riso, P., Zhan,g C., Shaposhnikov, S., Collins, A. 2023. Long-term cryopreservation of potassium bromate positive assay controls for measurement of oxidatively damaged DNA by the Fpg-modified comet assay: results from the hCOMET ring trial. Mutagenesis. 38(5):264-272. https://doi.org/10.1093/mutage/gead020. 

Møller, P., Azqueta, A., Rodriguez-Garraus, A., Bakuradze, T., Richling, E., Bankoglu, E.E., Stopper, H., Bastos, V.C., Langie, S.A.S., Jensen, A., Ristori, S., Scavone, F., Giovannelli, L., Wojewódzka, M., Kruszewski, M., Valdiglesias, V., Laffon, B., Costa, C., Costa, S., Teixeira, J.P., Marino, M., Del Bo’ C., Riso, P., Zhang, C., Shaposhnikov, S., Collins, A. 2023. DNA strand break levels in cryopreserved mononuclear blood cell lines measured by the alkaline comet assay: results from the hCOMET ring trial. Mutagenesis. 38(5):273-282.  https://doi.org/10.1093/mutage/gead019.

Collins, A., Møller, P., Gajski, G., Vodenková, S., Abdulwahed, A., Anderson, D., Bankoglu, E.E., Bonassi, S., Boutet-Robinet, E., Brunborg, G., Chao, C., Cooke, M.S., Costa, C., Costa, S., Dhawan, A., de Lapuente, J., Bo’, C.D., Dubus, J., Dusinska, M., Duthie, S.J., Yamani, N.E., Engelward, B., Gaivão, I., Giovannelli, L., Godschalk, R., Guilherme, S., Gutzkow, K.B., Habas, K., Hernández, A., Herrero, O., Isidori, M., Jha, A.N., Knasmüller, S., Kooter, I.M., Koppen, G., Kruszewski, M., Ladeira, C., Laffon, B., Larramendy, M., Hégarat, L.L., Lewies, A., Lewinska, A., Liwszyc, G.E., de Cerain, A.L., Manjanatha, M., Marcos, R., Milić, M., de Andrade, V.M., Moretti, M., Muruzabal, D., Novak, M., Oliveira, R., Olsen, A.K., Owiti, N., Pacheco, M., Pandey, A.K., Pfuhler, S., Pourrut, B., Reisinger, K., Rojas, E., Rundén-Pran, E., Sanz-Serrano, J., Shaposhnikov, S., Sipinen, V., Smeets, K., Stopper, H., Teixeira, J.P., Valdiglesias, V., Valverde, M., van Acker, F., van Schooten, F.J., Vasquez, M., Wentzel, J.F., Wnuk, M., Wouters, A., Žegura, B., Zikmund, T., Langie, S.A.S., Azqueta, A. 2023. Measuring DNA damage with the comet assay: a compendium of protocols. Nature Protocols. 18(3):929-989. https://doi.org/10.1038/s41596-022-00754-y.

Pilon, A., Avecilla, F., Rácz, B., Gátszegi, G.T., Spengler, G., Robalo, M.P., Enyedy, É.A., Garcia, M.H., Valente, A. 2023. Iron(II)-cyclopentadienyl compounds are cytotoxic against colon adenocarcinoma cell lines: Ethylenebis(diphenylphosphane) vs. triphenylphosphane. J Inorg Biochem. 249:112386. https://doi.org/10.1016/j.jinorgbio.2023.112386. 

Valdiglesias, V., Alba-González, A., Touzani, A., Fernández-Bertólez, N., Ramon-Pan, L., Moreda-Piñeiro, J., Yánez, J., Laffon B., Folgueira, M. 2023. Effects of zinc oxide nanoparticle exposure on human glial cells and zebrafish embryos. Int. J. Mol. Sci. 24, 12297. https://doi.org/10.3390/ijms241512297.

Brandão, F., Costa, C., Bessa, M.J., Valdiglesias, V., Hellack, B., Haase, A., Fraga, S., Teixeira, J.P. 2023. Multiparametric In Vitro Genotoxicity Assessment of Different Variants of Amorphous Silica Nanomaterials in Rat Alveolar Epithelial Cells. Nanotoxicology. 19:1-18. https://doi.org/10.1080/17435390.2023.2265481.

Lorenzo-López, L., Lema-Arranz, C., Fernández-Bertólez, N., Costa, S., Costa, C., Teixeira, J.P., Pásaro, E., Valdiglesias. V., Laffon, B. 2022. Relationship between DNA damage measured by the comet-assay and cognitive function. Mutat Res. Genet. Toxicol. Environ. Mutagen 883-884:503557. https://doi.org/10.1016/j.mrgentox.2022.503557

Maestro, M., and Seoane, S. 2022. The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands. Nutrients 14, 4927. https://doi.org/10.3390/nu1422492

Fernández-Bertolez, N., Lema-Arraz, Fraga, S., Teixeira, J.P., Pásaro, E., Lorenzo-López, L., Laffon, B. Valdiglesias V. 2022. Suitability of salivary leucocytes to assess DNA repair ability in human biomonitoring studies by the challenge-comet assay. Chemosphere. 307:136139. https://doi.org/10.1016/j.chemosphere.2022.136139

Robertina Giacconi, Blanca Laffon, Solange Costa, Armanda Teixeira-Gomes, Fabrizio Maggi, Lisa Macera, Pietro Giorgio Spezia, Francesco Piacenza, Alexander Bürkle, María Moreno Villanueva, Stefano Bonassi, Vanessa Valdiglesias, Joao Paulo Teixeira, Martijn E. T. Dollé, M. Liset Rietman, Eugène Jansen, Tilman Grune, Efstathios S. Gonos, Claudio Franceschi, Miriam Capri, Beatrix Grubeck-Loebenstein, Ewa Sikora, Wolfgang Stuetz, Olivier Toussaint, Florence Debacq-Chainiaux, Antti Hervonen, P. Eline Slagboom, Christiane Schön, Jürgen Bernhardt, Nicolle Breusing, Eduardo Pásaro Méndez, Laura Lorenzo-López, José Carlos Millán-Calenti, Ana Maseda, Mauro Provinciali, Marco Malavolta. 2022. Association of Torquetenovirus viremia with physical and cognitive frailty in three independent European cohorts Gerontology. https://doi.org/10.1159/000528169

Lucía Mato-López, Antía Sar-Rañó, Miguel Riopedre Fernández, María Luz Díaz-Prado, Adrià Gil, Ángel Sánchez-González, Natalia Fernández-Bertólez, Josefina Méndez, Vanessa Valdiglesias, Fernando Avecilla. 2022. Relationship between structure and cytotoxicity of vanadium and molybdenum complexes with pyridoxal derived ligands. Journal of Inorganic Biochemistry. 235:111937. https://doi.org/10.1016/j.jinorgbio.2022.111937.

Maurya, M.R., Maurya, S.K. Kumar, N., Avecilla, F., Gupta. P. 2022. Substituent Controlled Synthesis of Dioxidomolybdenum(VI) Complexes of N,N,N’,N’-Tetrakis(2-Hydroxyl-3,5-Disubstitutedbenzyl)-1,2-Diaminoethane, Their Trans-Metalation to Oxidovanadium(V) Complexes and Biocatalytic Applications. European Journal of Inorganic Chemistry, 23: 1-22. https://doi.org/10.1002/ejic.202200266

Valdiglesias V. 2022. Cytotoxicity and Genotoxicity of Nanomaterials. Nanomaterials. 12(4):634 https://doi.org/10.3390/nano12040634

Alena Opattova, A., Langie, S., Milic, M., Collins, A., Brevik, A., Coskun, E., Dusinska, M., Gaivão, I., Kadioglu, E., Lafon, B., Marcos, R., Pastor, S., Slyskova, J., Szilágyi, Z., Valdiglesias, V., Vodickaa, P., Bonassio, S., Godschalk, R. 2022. A pooled analysis of molecular epidemiological studies on modulation of DNA repair by host factors. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 876–877, 503447. https://doi.org/10.1016/j.mrgentox.2022.503447

Maurya, M.R. Chauhan, A., Verma, A., Kumar, U., Avecilla. F. 2022. Amine-functionalized titanium dioxide supported dioxidomolybdenum(vi) complexes as functional model for phenoxazinone synthase enzyme. Catalysis today 388-389: 274-287. https://doi.org/10.1016/j.cattod.2020.06.031

Teixeira-Gomes, A., Laffon, B., Valdiglesias, V., Gostner, J.M., Felder, T., Costa, C., Madureira , J., Fuchs, D., Teixeira, J.T., Costa, S. 2021. Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors. Antioxidants. 10(12), 1975. https://doi.org/10.3390/antiox10121975

Mannar R. Maurya, AC, Avecilla, F. 2022. Synthesis, characterization and biomimetic activity of heterogenized dioxidomolybdenum(vi) and analogous homogeneous complexes. ChemitrySelect 7(30): 1-19. https://doi.org/10.1002/slct.202202327

Costa, C., Assunção, R., Sequeira, D., Esteves, F., Valdiglesias, V., Laffon, B., Teixeira, J.P., Madureira, J. 2022. From trihalomethanes chronic daily intake through multiple exposure routes to cancer and non-cancer health risk assessment: Evidence from public Portuguese indoor swimming pools facilities using a probabilistic approach. Sci Total Environ 19;151790. https://doi.org/10.1016/j.scitotenv.2021.151790

Seoane S, Gogoi P, Zárate-Ruíz A, Peluso-Iltis C, Peters S, Guiberteau T, Maestro MA, Pérez- Fernández R, Rochel N, Mouriño A. 2022. Design, Synthesis, Biological Activity, and Structural Analysis of Novel Des-C-Ring and Aromatic-D-Ring Analogues of 1α,25-Dihydroxyvitamin D 3 . J Med Chem. 65(19):13112-13124. https://doi.org/10.1021/cas.jmedchem.2c00900

Bonassi, S., Ceppi, M., Moller, P., Azqueta., A., (…), Valdiglesias., V., (…), Dusinska., M., Collins., A. 2021. DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death. Scientific Reports. 11(1):16793. https://doi.org/10.1038/s41598-021-95976-7

Valdiglesias V., Fernández-Bertolez, N., Lema-Arranz, C., Rodríguez-Fernández, R., Pásaro, E., Reis, T., Teixeira, J.P., Costa C., Laffon, B. 2021. Salivary leucocytes as in vitro model to evaluate nanoparticle-induced DNA damage. Nanomaterials. 11(8):1930. https://doi.org/10.3390/nano11081930

Fernández-Bertolez, N., Brandao, F., Pásaro, E., Teixeira, J.P., Costa C., Laffon, B. Valdiglesias V. 2021. Suitability of the in vitro cytokinesis-block micronucleus test for genotoxicity assessment of TiO 2 nanoparticles on SH-SY5Y cells. Int. J. Mol. Sci. 22(16):8558. https://doi.org/10.3390/ijms22168558

Fernández-Bertólez, N., Azqueta, A., Pásaro, M., Laffon, B., Valdiglesias, V., 2021. Salivary leucocytes as suitable biomatrix for the comet assay in human biomonitoring studies. Arch. Toxicol. 31, 1-9. https://doi.org/10.1007/s00204-021-03038-8.

Laffon, B., Sánchez-Flores, M., Fernández-Bertólez, N., Pásaro, E., Valdiglesias, V. 2021. Applicability of flow cytometry γH2AX assay in population studies: suitability of fresh and frozen whole blood samples. Arch. Toxicol. 95(5):1843-1851. https://doi.org/10.1007/s00204-021-03009-z

Møller, P., Bankoglu, Stopper, H., Giovannelli, L., Ladeira, C., Gudrun, G., Gajski, G., Collins, A., Valdiglesias, V., Boutet, E., Perdry, Del Bo', C., Langie, S., Laffon, B., Dusinska, M., Azqueta, A. 2021. Collection and storage of human white blood cells for analysis of DNA damage and repair activity using the comet assay in molecular epidemiology studies. Mutagenesis. 23:geab012. https://doi.org/10.1093/mutage/geab012

Milić, M., Ceppi, M., Bruzzone, M., Azqueta, A., Brunborg, G., Godschalk, R., Koppen, G., Langie, S., Møller, P., Teixeira, J.P., Alija, A., Anderson, D., Andrade, V., Andreoli, C., Asllani, F., Bangkoglu, E.E., Barančoková, M., Basaran, N., Boutet-Robinet, E., Buschini, A., Cavallo, D., Costa Pereira, C., Costa, C., Costa, S., Da Silva, J., Del Bo´, C., Dimitrijević Srećković, V., Djelić, N., Dobrzyńska, M., Duračková, Z., Dvořáková, M., Gajski, G., Galati, S., García Lima, O., Giovannelli, L., Goroshinskaya, I.A., Grindel, A., Gutzkow, K.B., Hernández, A., Hernández, C.,. Holven, K.B., Ibero-Baraibar, I., Ottestad, I., Kadioglu, E., Kažimirová, A., Kuznetsova, E., Ladeira, C., Laffon, B., Lamonaca, P., Lebailly, P., Louro, H., Mandina Cardoso, T., Marcon, F., Marcos, R., Moretti, M., Moretti, S., Najafzadeh, M., Nemeth, Z., Neri, M., Novotna, B., Omar, F., Orlow, I., Paduchov, Z., Pastor, S., Perdry, H., Spremo- Potparević, B., Ramadhani, D., Riso, P., Rohr, P., Rojas, E., Rossner, P., Safar, A., Sardas, S., Silva, M.J., Sirota, N., Smolkova, B., Staruchov, M., Stetina, R., Stopper, H., Surikova, E.I., Ulven, S.M., Ursini, C.L., Valdiglesias, V, Valverde, M., Vodicka, P., Volkovov, K., Wagner, K.- H., Živković, L., Dušinská, M., Collins, A.R., Bonassi, S. 2021. The hCOMET project: international database comparison for results with the comet assay in human biomonitoring: Baseline frequency of DNA damage and effect of main confounders. Mutation Research – Reviews in Mutation Research. 787, 108371. https://doi.org/10.1016/j.mrrev.2021.108371

Laffon, B., Bonassi, S., Costa, S., Valdiglesias., V. 2021. Genomic instability as a main driving factor of unsuccessful ageing: potential for translating the use of micronuclei and nucleoplasmic bridges into clinical practice. Mutation Research – Reviews in Mutation Research. 787:108359. https://doi.org/10.1016/j.mrrev.2020.108359

Valdiglesias, V. Sánchez-Flores, M.; Fernández-Bertólez, J.; Au, W., Pásaro E.; Laffon, B.; 2021. Expanded usage of the Challenge-Comet assay as a DNA repair biomarker in human populations: protocols for fresh and cryopreserved blood samples, and for different challenge agents. Archives of Toxicology. 94:4219–4228.https://doi.org/10.1007/s00204-020-02881-5